收稿日期:2009-09-10
作者简介:刘青芝(1985- ),女,硕士研究生,制药工程专业
*
通讯作者:郭学平,男,研究员,硕士生导师,研究方向:微生物制药 E-mail:guo-xp@139.com
Progress on Biosynthesis andApplication of Sophorolipids
LIU Qing-zhi1
, GUO Xue-ping2*
,ZHU Xi-qiang2
(1. School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China;
2. Institute of Biopharmaceuticals of Shandong Province, Jinan 250101, China)
Abstract: In recent years, the biosurfactants with the advantages of biodegradability, low toxicity and Low
production cost have attracted extensive attentions and studies. Sophorolipids are surfactant compounds synthesized
by yeast. This review outlines the structures, fermentation and purification of sophorolipids, as well as its applications
in medicine, environmental protection, cosmetics and so on.
Key Words: sophorolipids; biosurfactant; fermentation; production; application
·综述·
52 食品与药品 Food and Drug 2009 年第 11 卷第11期物,分别生产出不同结构的槐糖脂(SL-p、SL-s、SL-o、
SL-l),并对它们进行物理性质的研究,发现在水溶性、临
界胶束浓度、界面张力方面均有较大差异,但最小表面张力
差异不大,且高浓度盐溶液、温度、pH等环境因素对其表
面活性影响较小.
O
O
O
O CH
CH3
(CH2)6
CH
CH
(CH2)7
COOHOH
OH
OH
CH2OR''
OH
OH
CH2OR'
1'
2'
3'
4'

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